Neuropathic pain is distinct from other types of pain. If a person breaks a bone, pain signals are carried via nerves from the site of the trauma to the brain. With neuropathic pain, however, pain signals originate in the nerves themselves.

In This Article:

How Neuropathic Pain Develops

In many cases, the nerves become damaged or dysfunctional after responding to an injury or trauma, causing hypersensitivity to pain. The nerves then send faulty signals of pain even when the injury has healed. The initial injury can occur in either the peripheral or central nervous system.

Neuropathic pain, or neuropathy, is a chronic condition, meaning it does not go away. Instead, the pain becomes the disease process. The terms sensory peripheral neuropathy and peripheral neuritis are sometimes used to describe neuropathy affecting the peripheral nerves.

See Chronic Pain As a Disease: Why Does It Still Hurt?

An estimated 7 to 10% of people have neuropathic pain.1Van hecke O, Austin SK, Khan RA, Smith BH, Torrance N. Neuropathic pain in the general population: a systematic review of epidemiological studies. Pain. 2014;155(4):654-62.

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When Back Pain Causes Neuropathy

Neuropathy can result from any type of pain that compresses or impinges on a nerve. A herniated disc, for example, could press against a nearby nerve, causing pain. Neuropathic pain originating from the back or spine may include:

See Radiculopathy, Radiculitis and Radicular Pain

Diabetes and regional pain syndrome (RPS), are common causes of neuropathy. Additional causes of include injury, disease, infection, exposure to toxins, and substance abuse. It is not always possible to pinpoint the cause.

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Why Early Treatment is Crucial

Early treatment is important, since more aggressive treatment may be needed if symptoms are not addressed soon.

See Treatment Options for Neuropathic Pain

Over time, exposure to significant pain can cause changes to the central nervous system that make the body become more sensitive to even slight touch—a phenomenon known as central sensitization.

See Medications for Neuropathic Pain

As with other types of chronic pain, delays in treatment may also make other health problems more likely. Depression, anxiety, difficulty sleeping, and an inability to work and take part in other activities are some health issues associated with untreated neuropathy.

See Additional Treatments for Neuropathic Pain

  • 1 Van hecke O, Austin SK, Khan RA, Smith BH, Torrance N. Neuropathic pain in the general population: a systematic review of epidemiological studies. Pain. 2014;155(4):654-62.

Dr. Ralph Rashbaum is an orthopedic surgeon and co-founder of the Texas Back Institute. He has more than 40 years of experience in surgical and non-surgical techniques to treat back and neck conditions. Dr. Rashbaum is active in medical research.

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